Regulatory Intelligence

Analysis from the AI device front line.

Technical, authoritative breakdowns of how FDA regulates AI-enabled medical devices — written for the people who have to get cleared.

How to find AI device predicates in the FDA 510(k) database

A working method for tracing the predicate chain behind any cleared AI device — what the 510(k) summary actually tells you, where the database falls short, and how to reconstruct lineage that FDA never publishes directly.

FDA AI Medical Device Product Codes — Complete List (QMF, OZO, QNC and More)

Every product code FDA has created for AI and ML medical devices — what each covers, when it was established, and how many devices have cleared under it.

8 min

How Long Does FDA 510(k) Clearance Take for AI Devices? 2025 Data

Real clearance timeline data for AI medical devices — median review times by product code and indication, based on 950+ cleared devices.

7 min

How to Use a De Novo as a Predicate for Your 510(k) AI Device Submission

De Novo decisions create new product codes and establish special controls — and they can be powerful predicates for 510(k) submissions.

9 min

FDA AI Medical Device Regulations in 2025 — What's Changed and What's Coming

A complete overview of FDA's current regulatory framework for AI devices — final guidance, draft guidance, enforcement trends, and what to watch for.

10 min

PCCP vs 510(k) Supplement for AI Algorithm Changes — When to Use Each

When your AI algorithm changes post-clearance, should you file a PCCP, a Special 510(k), or a Traditional supplement? A practical decision framework.

8 min

How to Build Competitive Intelligence from FDA 510(k) Public Data

Every 510(k) clearance is a public document. Here's how to systematically extract competitive intelligence from FDA's public records.

9 min

FDA Warning Letters Against AI Medical Devices — What They Reveal

An analysis of FDA warning letters involving AI diagnostic devices — what violations FDA is acting on and what to avoid.

8 min

MAUDE Adverse Event Reports for AI Medical Devices — What the Data Shows

An analysis of MAUDE reports for cleared AI devices — what types of events are being reported and what it means for regulatory strategy.

7 min

De Novo vs 510(k) for AI Medical Devices — Which Pathway Is Right for You?

Choosing between De Novo and 510(k) is one of the most consequential regulatory strategy decisions you'll make. Here's a practical framework.

9 min

How Viz.ai and Aidoc Built a Regulatory Clearance Moat

An analysis of how leading AI radiology companies used predicate strategy and PCCP to build compounding regulatory competitive advantages.

10 min

The FDA 510(k) AI medical device clearance list, explained

What's actually in FDA's AI/ML-enabled device list, why the static spreadsheet falls short, and how to read it like a database.

9 min

What is a Predetermined Change Control Plan (PCCP)?

FDA's mechanism for approving algorithm changes without a new submission — what qualifies, what doesn't, and the patterns in approved plans.

11 min

FDA De Novo AI device product codes: a complete map

Every De Novo grant that created a new AI product code, and what its special controls mean for the devices clearing into it.

13 min

FDA AI medical device guidance documents, 2024–2025

The action plans, draft guidances, and discussion papers shaping AI regulation — and what each one changes in practice.

12 min

FDA enforcement actions on AI diagnostic devices

What the warning letters reveal about FDA's posture on AI diagnostics, and where the agency is drawing its lines.

10 min

The SaMD regulatory pathway at FDA: a practical guide

How Software as a Medical Device moves through FDA, from classification to clearance, with the decisions that matter most.

15 min

Read the data behind the analysis.

Every post is grounded in the same dataset that powers the platform.

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